![]() "Apparently the deletion is somehow associated with adaptation during this jump from animal to human," she says.Īltogether, this genetic data suggest that Vlasova and her colleagues are catching this new coronavirus early on in its journey in people, while it's still trying to figure out how to infect people efficiently - and possibly, before it can spread from person to person and trigger a big outbreak. And it may be a key step required for coronaviruses to make the jump into people. This deletion, she believes, helps the dog virus infect or persist inside humans. very soon after its introduction into the human population," Vlastova says. ![]() "It's a mutation that's very similar to one previously found in the SARS coronavirus and in SARS-CoV-2. That specific deletion, she says, isn't present in any other known dog coronaviruses, but it is found somewhere else: in human coronaviruses. "We did discover a very, very unique mutation - or deletion - in the genome," Vlasova says. Then she found a disturbing clue about the virus's future. "The majority of the genome was canine coronavirus," she says. But it likely jumped directly from dogs into people. ![]() From the virus's gene sequences, she could see that the virus had likely infected cats and pigs at one point. With a lot of virus on hand, Vlasova could decode its genome. Goats and Soda Visual Explainer: Why Some Coronavirus Variants Are More Contagious Than Others This virus may be the eighth coronavirus known to cause disease in people, the team reports Thursday in the journal Clinical Infectious Diseases. In the first batch of samples tested last year, Gray and Xiu found evidence of an entirely new coronavirus associated with pneumonia in hospitalized patients - mostly in kids. Xiu not only rose to the challenge, but the tool he created worked better than expected. So he challenged a graduate student in his lab, Leshan Xiu, to make a more powerful test - one that would work like a COVID-19 test but could detect all coronaviruses, even the unknown ones. They generally focus on known viruses," says Gray, an infectious disease epidemiologist at Duke University's Global Health Institute. Gregory Gray started to wonder whether there might be other coronaviruses out there already making people sick and threatening to trigger another. It tells whether one particular virus - SARS-CoV-2 - is present in a person's respiratory tract, and nothing else. When the COVID-19 pandemic first exploded, Dr. The test for COVID-19, he says, is extremely limited. The problem was that he didn't have a tool to look for them. Goats and Soda How Do We Stop The Next Pandemic? Here's A New Strategy
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